Science: You Might Be Slightly Conscious Under Anesthesia!
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Video & Audio: Nelson Mandelas support for Jews
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[Notice the precision of our race and the levels of detail they dig into. This is a topic we will return to, and its critical importance. Jan]
It’s the stuff of nightmares: regaining consciousness while under general anesthesia.
But according to a group of doctors in Finland, it may be that we never fully lose consciousness under anesthesia. Two new studies, both published in the July issue of the British Journal of Anaesthesia, suggest that the brain is still partly conscious under the influence of anesthetics, even though the person who has taken the drug isn’t reacting or seemingly aware.
“The brain is working more than we have thought during general anesthesia,” said Dr. Harry Scheinin, an anesthesiologist at the Terveystalo Pulssi Hospital and adjunct professor at the University of Turku, both in Finland. But this “is not necessarily a problem.” [Social Surgery: A Gallery of Live-Tweeted Operations]
In both studies, researchers used data collected from 47 adults who were placed under anesthesia. The adults received one of two common anesthetics used in surgery: dexmedetomidine and propofol. The researchers gave the participants low doses of the drugs — just enough for them to lose responsiveness.
While still under the influence of the anesthetics, in one of the studies, the researchers shook the participants and spoke loudly to wake them up, and then asked them what their experience had been like. All the while, the researchers recorded the participants’ brain activity with a device called an electroencephalogram (EEG).
Most of the participants reported experiencing dreams mixed in with reality. These were pretty typical dreams, said Scheinin, who co-led the research effort. “There are people who thought [a] couple of years ago, that if you are dreaming during general anesthesia or surgery, … the anesthesia [dose] may be too low, but I don’t agree. I think dreaming can be relatively common and normal in surgical anesthesia.”
It’s possible that “general anesthesia can be [closer] to normal dreaming or sleeping than we have previously thought,” Scheinin added. (It is thought that a dreaming person, for example, is partly conscious, he said.)
In a second experiment that was also published in the first study, the researchers played unpleasant sounds while the participants were under anesthesia. Once the participants were awake, the researchers had them listen to more unpleasant sounds — some of which had been played to them while under anesthesia. The people reacted faster to the sounds that had been played while they were under anesthesia than the ones they hadn’t heard before. Again, this suggests the brain is somehow processing these sounds, even while under anesthesia, Scheinin said.
The second study focused on the results of yet another experiment done when the participants were under anesthesia. In this experiment, the participants were played a recording of regular sentences that ended with a really bizarre word — one that clearly didn’t belong in the sentence, such as “The bear walks on the moon” instead of “The bear walks in the forest.”
When people are awake, hearing that unexpected word usually causes a greater response in brain activity than an expected word would, Scheinin told Live Science. The researchers found that when the people were under anesthesia, however, their brain activity looked the same, regardless of which type of sentence was played — in other words, their brains couldn’t tell the difference between normal and weird sentences. But curiously, in the people given dexmedetomidine, the researchers observed a spike in brain activity that coincided with the end of the sentences.
Scheinin said that he thinks that both types of words — normal and bizarre — might have triggered this spike because the brain might lose context or expectations while under anesthesia. For example, it may be that the people under anesthesia can’t remember the beginning of the sentence by the time they hear the end, or they can’t integrate the words into sentence form, he said. But the spike in activity at the end of the sentences suggests that they are still hearing and processing the sentences.
Once the people were awake, however, none of them remembered what they heard.
These studies “confirm that consciousness is rarely ever lost,” said Allan Leslie Combs, the director of the California Institute of Integral Studies Center for Consciousness Studies, who was not involved with the new research. But what is commonly lost is memory, Combs said, which is what the second study suggested. In other words, even though a person may not fully lose consciousness while under certain anesthetics, that person does lose the memories that occur at this time.
“It’s worth pointing out that these studies all use very light anesthesia,” Combs told Live Science — much lighter than what would be used when a person is having surgery. So, it’s possible that the experience could be different for the levels of anesthesia used in surgery, he added.
Scheinin acknowledged that the doses of anesthesia used in the studies were light but thinks the results could also hold true for normal levels of anesthetics. However, there are many other drugs that are thrown into the mix during normal surgery, including opioids and muscle relaxants, which could also alter the results, Scheinin said.
The new findings could help develop technologies or drugs to eliminate what doctors call “unintended awareness,” Scheinin said, referring to terrifying stories of unlucky individuals who somehow end up awareduring surgery but are unable to notify the doctors. The phenomenon is rare — it occurs in only about 1 in 1,000 people — but that doesn’t mean researchers shouldn’t try to solve it, he added.
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